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Methylation analysis
DNA methylation plays a critical role in the regulation of gene expression and has been implicated in the etiology of many human diseases including cancer.
Array-based Methylation Analysis
IntegraGen uses Illumina Infinium Methylation assays for quantitative methylation measurement at single CpG site level.
| Beadchips | Minimum batch of samples | Coverage |
| HumanMethylation27 | 24 | 27,578 CpG loci, >14,000 genes |
| HumanMethylation450 | 24 | > 450,000 methylation sites |
IntegraGen's Service
IntegraGen provides a complete service including:- DNA sample reception and QC
- Bisulfite conversion
- Genotyping analysis using the Illumina Infinium technology with the HumanMethylation27K or 450K beadchips
- Data quality control
- Delivery of methylation value for all CpG sites (value between 0 and 1) upon tabular tab
- Delivery of 'Genome studio' project file for data analysis with Genome studio software
Illumina CSPro
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