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Methylation analysis

DNA methylation plays a critical role in the regulation of gene expression and has been implicated in the etiology of many human diseases including cancer.

Array-based Methylation Analysis

IntegraGen uses Illumina Infinium Methylation assays for quantitative methylation measurement at single CpG site level.

Beadchips Minimum batch of samples Coverage
HumanMethylation27 24 27,578 CpG loci, >14,000 genes
HumanMethylation450 24 > 450,000 methylation sites

IntegraGen's Service

IntegraGen provides a complete service including:
  • DNA sample reception and QC
  • Bisulfite conversion
  • Genotyping analysis using the Illumina Infinium technology with the HumanMethylation27K or 450K beadchips
  • Data quality control
  • Delivery of methylation value for all CpG sites (value between 0 and 1) upon tabular tab
  • Delivery of 'Genome studio' project file for data analysis with Genome studio software

 

 

Illumina CSPro

 

Illumina CSPro

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